Editorial / Featured Articles / Industry News

Peptides – What Are They + How Do They Work

Peptides! We hear about them; we use them, and we know the importance and the efficacy they can have on the skin. But what are they? How do they work? How do they improve the efficacy of a skincare product?  

Putting the “Pep” in Peptides

Peptides are molecules consisting of short strings of amino acids (approximately between 2 to 50 strings), linked by peptide bonds. Whereas longer chains of peptides form proteins.

Due to the larger size of protein molecules, they cannot be appropriately absorbed in the skin. Peptides, on the other hand, being smaller, can easily penetrate the skin, offering a range of skin care benefits. This attribute is one of the reasons peptides are skincare stars.


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Peptides Do The Work

When peptides are formulated in skincare, those products improve multiple skin issues. Peptides act as messengers. They work at the cellular level; each having their own qualities that target specific actions in the body. The body recognizes the peptide messenger as a signal to perform a specific function, often a “healing” action. 

The specific action is determined by the sequence and length of amino acids in a peptide. There are various types of peptides including: Dipeptides (two amino acids), Oligopeptides (three to ten amino acids), and polypeptides (more than ten amino acids). The peptide’s role can often be altered to amend their function and signals.

Let’s take an example we’re all familiar with – aging. As we age (even prematurely aging), we lose collagen and elastin leading to wrinkling and sagging skin. When applying skincare with peptides, you introduce the peptide’s qualities onto the skin. This acts as if it is “tricking” the skin into thinking there has been an injury/wound. And on that note…

More Than Anti-Aging

While peptides products are commonly known for fighting the signs of aging, peptides are just as effective and beneficial in addressing other skin concerns. There are a multitude of peptides, with each having their own function, playing a specific role in the care of skin – and not all of them for anti-aging! Peptides can help ease inflammation, improve skin hydration, calm redness, help protect from damaging environmental aggressors and so much more! Let’s find out…

Talking Peptides

So, depending on the peptide, the signal it gives addresses specific skin reactions such as helping hydrate, smooth the skin, decrease wrinkles, firm, and brighten the skin, and help with hyperpigmentation and sensitive skin concerns.

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Best Peptides in MAD Skincare  for 4  Popular Skin Types

Ideal For All Skin Types 

The environment’s more damaging to skin than ever before. Pollution, stress, and a poor diet all contribute to premature aging and even enhance current signs of aging.  Your skin needs a shield to protect against these environmental aggressors.

Peptides addressing environmental concerns and premature aging include:

M.A.D’s Pollution Defense Peptide: Enhances the function of skin, helping eliminate toxins and minimize damaging effects of physical and emotional stress. It also guards against free radical damage.

Shield Bact Peptide: A hexapeptide with broad spectrum antimicrobial activity mimicking and enhancing the natural antimicrobial properties of the skin. With its  natural ability to fight bacteria, it serves as a powerful protector against everyday pollutants.

You can find these peptides in M.A.D Skincare’s Environmental Concern products including M.A.D Daytime Defense Shielding Moisturizer and Wrinkle Repellent Environmental Protection Serum.

Ideal For Brightening

Dull skin, hyperpigmentation, age spots, and sunspots, peptides with brightening properties can address these skin concerns and leave skin radiant!

Peptide addressing skin brightening:

ß-White™ is an innovative encapsulated whitening peptide and acts as a key ingredient to a safe, progressive, and effective lightening impact

You can find ß-White™ in many of M.A.D’s Brightening Concern Products including Spot On Targeted Skin Brightening Serum and Illuminating Daily Moisturizer.

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Contribution by Michael Contorno, President, CEO M.A.D Skincare

Michael has over 20 years of experience in the cosmeceutical skin care space. He continuously remains
engaged in the development of the next generation skincare products that will entice the consumer,
enchant the professional, and embrace the newest and most exciting materials that will captivate and
invigorate the skincare market.

His expertise includes:

  • Product development
  • Innovative formulation development
  • Brand development
  • Brand and Product education
  • Manufacturing enterprise management
  • supply chain and logistics development

As a founding member of M.A.D Skincare Michael has developed the core philosophy of the brand as
well as created a national training program designed to educate skin care professionals on how to
effectively treat specific skin concerns. Our mission at M.A.D Skincare is to deliver the best possible
products for your individual skin concerns.

Ideal for Delicate/Sensitive

Red, irritated, inflamed, and/or dehydrated skin needs peptides to calm skin, diminish redness, hydrate, heal, soothe, and rejuvenate.

Peptides addressing delicate/sensitive concerns include:

M.A.D’s Soothing Peptide Complex: A blend of powerful peptides offering superior skin rejuvenation benefits and aiding in tissue regeneration.

Palmitoyl Tripeptide-8: Essential for healing, this peptide significantly reduces skin’s inflammatory responses and minimizes swelling and irritation of dry inflamed skin.

Neutrazen™: This lipopeptide can help prevent and reverse signs of inflammation and calm and soothe irritated skin. It also helps maintain and restore a normal skin sensitivity threshold.

You can find these peptides in M.A.D Delicate Concern Products including Redness Rescue, Delicate Soothing Night Cream, and Delicate Skin Calming Mask.

Ideal for Anti-Aging

Sagging skin? Lines? Wrinkles? Dull Skin? Ah, the changes that come as we age. Collagen production decreases and elastin fibers regress (causing sagging and wrinkles) and loss of elasticity, rough skin texture, compromised skin barrier (hello, dehydration and dry skin) and uneven skin tone.

Anti-Aging Peptides addressing signs of aging include:

Multi Peptide Anti-Aging Complex: Offers excellent skin rejuvenating benefits and skin regeneration, this potent peptide complex helps remodel the skin, minimize the appearance of wrinkles, and improve elasticity.

Oligopeptide: A hyaluronic acid booster, this peptide helps to stimulate synthesis of collagen and help rebuild the skin’s matrix offerings skin texture that is more refined, firmed, and toned.

Matrixyl® 3000: A Palmitoyl pentapeptide-4 activates messengers for reconstruction and repair. This peptide provides a noticeable improvement in wrinkle density, wrinkle depth, volume, and roughness.

You can find these peptides in M.A.D’s Anti-Aging Concern including Transforming Daily Moisturizer, Eye Transformation Serum, and Youth Transformation Age Corrective Serum.

Salmon Overy Peptides, found in M.A.D’s Luxe Line, is formulated with a combination of 20 ultra-effective amino acids including Asparagine which acts as a water-binding agent, providing antioxidant properties, protecting from free-radical damage, and reducing signs of aging; and Threonine known for its ability to provide anti-aging and hydration benefits.

Peptides are essential to the skin’s structure and function. They appear in every human cell and act as an integral role in how the body (including skin!) functions, taking on the role of a biologic messenger. Don’t miss the call!

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