Exosome facial product ingredient technology is one of the hottest topics in the medical + spa skin care industries. L+A first saw exosome facial products for treatments from Benev at AMWC – Miami in 2023. Then in 2024 exosomes burst onto the global market showing up from several different brands at AMWC – Miami 2024, at IMCAS – Paris 2024, at AmSpa – Las Vegas 2024, and then at Nelly De Vuyst Training – Montreal 2024.
The science of exosome facial product ingredient technology is still somewhat of a mystery to many. L+A reached out to Dr. Andrew R. Christie-Schwarz PhD, for an explanation.
Exosome Facial Product Ingredient Technology Explained
“An exosome is a nano (30-200nm), extracellular vesicle (a fluid-filled structure enclosed by a lipid bilayer) found in fluid-secreting cells. They can be thought of as tiny fluid-filled bubbles which are released by a cell. They are incredibly small and are approximately 1/100th – 1/1000th of the cell size they are secreted from.*1
Exosomes contain biomolecules including proteins, lipids, and nucleic acids (naturally occurring chemical compounds that serve as the primary information-carrying molecules in cells). These include elements of ribonucleic acid (RNA). They act as shuttles or messengers from stem cells to other cells for certain genetic information and proteins.*2 The biomolecules found in exosomes harvested from mesenchymal stem cells, play significant roles in intercellular communication and promote tissue healing, regeneration, and repair.*3 The cell-to-cell communication can be facilitated between near and distant cells.”
Dr. Andrew R. Christie-Schwarz PhD, Paris (France). Clinical Director, Equipmed Aesthetics
The 2024 L+A Report: Using Science in Medical + Spa Skin Care Treatments
The “2024 L+A Report: Using Science in Medical + Spa Skin Care Treatments” showcases exosome facial ingredient technology as one of the five ways that medical + spa skin care professionals can leverage science in their treatments and the products that they recommend for home care.
5 Ways To Leverage Science in your Medical or Spa Skin Care Practice
Thanks to the brands listed below for sponsoring this content, so that L+A can bring the most current scientific advancements to our community of medical + spa skin care professionals.
1 Science of Growth Factor + Exosome Facial Treatment Products
L+A is proud to work with three global companies that have access to some of the most cutting-edge technology on the global market. One Korean brand has two all-new exosome facial treatment products. Another is a Belgian brand that is using plant exosomes and stem cells in an all-new collection. Finally, a Spanish skin care brand uses growth factors in their extensive Lab Series for medical + spa skincare professionals to use in their treatments.
2 Science of Medical + Spa Peels
There is so much science in the medical + spa chemical peels. There’s an all-new two-step treatment that is showcasing unparalleled results. We’re also showcasing a Guide on Needling + Chemical Peels that you don’t want to miss. We found a wonderful peel that will help clear your clients’ skin! Finally, we found a high-tech solution for sun-damaged skin repair.
3 Medical + Spa Science-Based Summer Treatments
Looking to add a little science to your medical + spa skin care treatment menu this summer? Try this, “Beat The Heat Facial”! You can also look to offer a highly-advanced, age management treatment that will deliver results because of an innovative delivery system!
4 Medical + Spa Skin Device Science
Stop the presses! We found an all-new Radiofrequency, Microcurrent hand-held device!! We are also proud to showcase one of the most unique anti-hyperpigmentation devices that will help you literally zap away dark spots!
5 Medical + Spa Skin Post Procedure Home Care Science
Let’s keep it real and honor the fact that if patients aren’t compliant with home, nothing that is done in treatment is going to be as effective as it could be if home care was habitual.
Another all-new find is a hyperpigmentation product that you must recommend if you’re doing any in-clinic treatments to even out skin tone. This product is from one of the industry’s most respected product formulators! We have evolved as an industry and now we do more advanced treatments year-round – don’t miss this incredible post-procedure sunscreen!
2024 Medical + Spa Skin Care Treatments
Biodroga Recontouring Power Needling Treatment Guide with Combined Acids
In this Mini Intro, Biodroga Medical Institute will demonstrate their methods of combining Mixed Acid Peels with Microneedling/Nanoneedling and Ultrasound to create high-performance treatments backed by the power of biotechnological active ingredients.
Discover everything you would want to know about acids as we do a deep dive into the different types of Acids and our great “Mix and Match” Concept that allows the Skincare Specialist to design the perfect individualized treatment for their clients.
Don’t miss this opportunity to learn from an industry expert!
All-New Even Tone by Dermastart
Try It at Las Vegas IECSC Booth 222!
Backed by years of proven science in their product formulations Dermastart leverages high-performance ingredient technology in their newest product for medical + spa skin care professionals in all-new Even Tone! Dermastart recommends that patients apply Even Tone every night or as directed by their physician.
Even Tone is a multitasking HQ FREE cream that restores the natural skin tone by brightening unwanted sunspots and other irregular pigmentation concerns.
This combined formula contains professional-strength ingredients and bioactive botanicals to treat the most sensitive of skin.
Even Tone helps aid Post-inflammatory hyperpigmentation (PIH), a common type of hyperpigmentation.
Formulated using a liposomal preparation combining powerful whitening ingredients with antioxidants for a strong brightening effect. Combining multiple ingredients and antioxidants together helps stabilize oxygen, this process inhibits both the tyrosinase activity and the activation of this enzyme.
Formulation Spotlight: Glutathione, Tranexamic Acid, Azelaic Acid, Niacinamide, Quercetin, Engelhardtia Chrysolepis Leaf Extract, Diacetyl Boldine, Palmitoyl Tripeptide-8, Niacinamide Vitamin B3 and Vitamin C.
All-New Renew Dermal Solution by FACTORFIVE
Introducing a revolution in professional treatments, Renew Dermal Solution 2 Step System!
Elevate your practice with FACTORFIVE Renew Dermal Solution, a cutting-edge treatment designed to redefine the chemical peel experience for your clients. Developed with the needs of medical and spa skin care professionals in mind, FACTORFIVE’S patent-pending two-step protocol offers a revolutionary approach to addressing common skin concerns.
Step One
Introduces RDS1 Penetrating Solution, a meticulously crafted blend of TCA, hydrogen peroxide, Kojic acid, and peptides, engineered to provide effective exfoliation, brightening, and rejuvenation without the inconvenience of visible peeling or extended downtime.
Step Two
FACTORFIVE’S soothing RDS2 Calming Solution harnesses the power of human stem cell factors, tripeptide-1 copper acetate, and botanical extracts to calm inflammation, promote healing, and protect the skin post-treatment.
Watch a video explaining the all-new FACTORFIVE RDS on the L+A Mobile App. Download the app, login, and search FACTORFIVE.
Expert Lab EGF Complex + Liquid Collagen Complex from Germaine De Capuccini
The all-new EGF Complex and Liquid Collagen Complex from Germaine De Capuccini’s Expert Lab Line are two of the most clinically advanced age management products available. This is due, in part, to their proprietary HLG Nanopolymer delivery system that multiplies the effectiveness of the active ingredient (clinically proven efficacy) by SIX TIMES!
EGF Complex
EGF Complex is a non-invasive method to achieve regenerated skin, thanks to the exclusive growth factor ingredient technology, which improves the active cell regeneration mechanism, enhancing collagen and elastin production. Germaine De Capuccini uses Plant-derived growth factors, specifically, TGFβ2 and Plant-EGF.
Growth Factors are vital allies in skin health, thanks to the EGF Complex, which increases collagen, elastin, hyaluronic acid, fibronectin, and other matrix components
Liquid Collagen Complex
The Liquid Collagen Complex immediately tightens based on the collagen liquid thread technique. In addition to providing an immediate lifting and plumping effect; it rejuvenates the skin for up to 10 years*. *Studies conducted on the raw material.
Germaine De Capuccini tells L+A “This is not a temporary fix but a long-term solution for the skin’s health and beauty. Liquid Collagen Complex is a new Next-generation Peptide Complex with excellent benefits. It increases collagen production and formation and improves its density.”
Germaine De Capuccini touts their new-generation Peptide complex and Proteoglycans as the key factors in the success of this product.
Sun Damaged Skin Repair with High Tech Solutions from ID Skin
“If you have patients who tanned a lot in their youth or barely wore sunscreen, it’s not too late to repair their skin.
Begin with a Professional ID SKIN Lactic Acid Peel Treatment. Your clients will benefit from an immediate deep exfoliation peel. The ID Skin Peel protocol begins with ID Skin Peel Prep Solution and after the peel is removed, the Peel Neutralizer.
Lactic acid is an anti-wrinkle and pigmentation-lightening ingredient found in over-the-counter (OTC) and professional-grade skin care products. Perfect for post-sun damage. Derived from milk, lactic acid belongs to a class of anti-aging ingredients derived from milk, in the group of alpha-hydroxy acids (AHAs), and requires less downtime.
Medical + spa skin care professionals should have their patients use serums at home. The advancements in ingredient technology have given the medical + spa skin care professional topical Vitamin C, Retinoids, Kojic Acid, Peony, and Arbutin. Because these ingredients have a small molecular structure they will penetrate deeply and actually will fade hyperpigmentation and wrinkles. These key ingredients are found in ID SKIN’s Clarity Brightening Serum.” Carol, ID Skin
All-New Collagen Collection from Nelly De Vuyst
All-New Collagen Collection Featuring Exosomes and they’re launching them in the U.S. at the Las Vegas IECSC. Visit them at booth 719 to get more information!
“I’ve used both of these products and am in love! My skin is plump, hydrated, and dewy! The Sheet Mask is truly remarkable and the Intense Gel is more like a cream but dissolves into the skin like a gel – very unique.” Barry Eichner
Collagen Sheet Mask
Rich in collagen and hyaluronic acid, this gel helps to improve the elasticity and suppleness of the skin, allowing for firmer, smoother, and softer skin. The contours of the face are redrawn. To complete this synergy, the collagen mask uses exosome technology. This innovation harnesses the anti-inflammatory benefits of Centella Asiatica, accelerating cell regeneration and stimulating natural collagen production, enabling our gel cream to act on skin collagen on two levels. To complete this formula, prebiotics and antibacterial compounds were used, helping to preserve the balance of the skin flora and prevent imbalances.
Collagen Intense Gel
This antioxidant-rich formula counteracts the harmful effect of free radicals on the skin and limits the appearance of wrinkles, fine lines, and pigment spots. Antioxidants also help to fade the appearance of dark spots for a more even skin tone. The skin regains its radiance. Rich in collagen and hyaluronic acid, this gel helps to improve the elasticity and suppleness of the skin, allowing for firmer, smoother, and softer skin. To complete this synergy, our collagen gel uses exosome technology. This innovation harnesses the anti-inflammatory benefits of Centella Asiatica, accelerating cell regeneration and stimulating natural collagen production, enabling our gel-cream to act on skin collagen on two levels. To complete this formula, prebiotics and antibacterial compounds were used, helping to preserve the balance of the skin flora and prevent imbalances.
ISOV Exosome LLT Pro Solution From Pure Pro Aesthetics
Exo LLT Pro Solution is a collection of two different exosome ampoule kits. These unique solutions are used with devices such as ultrasound, HIFU, electrical devices, and LED light therapy. Read The Pure Pro Aesthetics Press Release
Tri Fills Solution
Tri Fills Solution 5 ml *5 vials eachA brightening and anti-aging ampoule with 8 target-specific ingredients such as Niacinamide, Tranexamic acid, Bisabolol, multiple forms of Ascorbic Acid, Glutathione for brightening, 7 plant exosomes, Galactomyces fermented filtrate, Super Centella and Colloidal Gold.
AC Fills Solution
AC Fills Solution 5ml*5 vials each – An ampoule designed for oily and acne-prone skin types. With patented active and soothing ingredients that both protect and repair skin. These activities are encapsulated in HD Ethosomes that protect and improve the inner skin environment. This solution contains an acid blend of Malic, Ascorbic, Citric, Tartaric, and Salicylic acid, 7 plant exosomes, Galactomyces fermented filtrate, Cyanocobalamin, and Colloidal Gold.
Beat The Heat Treatment + Overnight Recovery Mask by Roccoco Botanicals
Leave it to Jacine Drummond to use the science of ingredient technology to create a summer-centric treatment that medical + spa skin care professionals can use in their treatment room all summer long!
Jacine designed Roccoco’s Beat the Heat treatment to soothe and rebalance skin as it faces the challenges that increased temperature and humidity bring. The star of the show is the Overnight Recovery Mask.
The increased heat and humidity often bring inflammation, a disrupted barrier, and an imbalanced microbiome all leading to skin that is much more prone to irritation, flushing, and just generally feeling uncomfortable and hot!
Rococo Botanical’s Chrysanthemum & Rose Mask instantly cools the skin, acting like a cool compress, and contains true rose essential oil to provide calming and soothing to irritated/irritable and heat-flushed skins.
The Overnight Recovery Mask is applied to the skin at the end of the treatment. This mask does it all. It instantly soothes irritation and inflammation, rebalances the microbiome, reduces redness, repairs the barrier, and massively hydrates.
Especially important in the summer, though, the Overnight Recovery Mask prevents the heat activation of transient receptor potential vanilloid (or TRPV) channels in the skin that exacerbate cell death and inflammation. When you use Overnight Recovery Mask, you are quite literally letting your skin beat the heat!
“This mask feels amazing and provides instant soothing. When left on overnight, you’ll wake up with dewy, hydrated skin that is GLOWING!” Jenni Nagle
Evanescent Mask Treatment from Sesha Skincare
Medical and spa skin care professionals can now leverage a patented delivery system and highly advanced scientific ingredients in a brightening and hydrating treatment. The Evanescent Sheet Mask Treatment has three main components, each designed to target hyperpigmentation, infuse hydration, brighten overall skin tone, and calm and reduce redness.
The entire treatment uses Sesha Skincare’s proprietary P.E.T Technology Delivery System which enables penetration of all ingredients to the Basal layer!
The Evanescent Sheet Mask Treatment from Sesha Skincare will give you a glow and plump skin. The first step is a 10-minute massage with the Sesha Skincare Clarifying Serum. This serum contains ingredients that target pigmentation and reduce inflammation. The second is the application of the Seaweed Polysaccharide Sheet Mask to the skin over the Clarifying Serum. The third step is to apply the Australian Seawater Activator over the sheet mask. The mask will miraculously dissolve into a light gel. You then remove it with warm towels. This also produces a healthy glow and increases moisture in the skin.
“LOVE this treatment! It quite literally dissolves into fine lines and wrinkles to plump them up! (Pro Tip: set your camera up to record this one in action…it creates great IG content!)” Jenni Nagle
Clear Skin Peel with Lemon Lightening Serum by Sorella Apothecary
Over the past few years, Sorella Apothecary has made tremendous advances in the amount and type of advanced chemical peels that they offer to medical + spa skin care professionals to use in their practices.
We reached out to them and asked for a chemical peel that showcased some incredible science and they did not disappoint. They suggested we look at their Clear Skin Peel which is a cocktail of several acids designed to – clear the skin.
“Sorella Clear Skin Peel heals existing blemishes and prevents future breakouts while reducing post-inflammatory hyperpigmentation. Key ingredients featured are 15% mandelic acid, 10% lactic acid, and 2% phytic acid. This peel has a pH of 2.62 and self-neutralizing so no need to remove it from the skin after application.” Sorella Apothecary
In order to continue the process of keeping the skin bright and clear, Sorella also suggested their Lemon Lightening Serum for daily home care. “Watch sunspots, hyperpigmentation, redness, and inflammation fade away thanks to this serum’s lightening trifecta approach. Natural lighteners and skin brighteners leave you with calm and even skin.” Sorella Apothecary
“I’ve used many products by Sorella Apothecary and have had a few of their peels. I particularly loved the Lemon Lightening Serum, it’s lightweight and has a gorgeous glide. My skin soaked it in! It’s a must-try!” Barry Eichner
Post Procedure Sunscreen from TIZO
If you’re looking for an ideal post-procedure sunscreen – medical + spa skin care professionals can trust TIZO to provide the highest quality, scientific ingredients in their sunscreen products.
The TIZO® Ultra Zinc Body & Face Sunscreen is ideal for post-procedure! It is a moisturizing all-mineral sunscreen suitable for all skin types and tones. Sheer and virtually invisible, it smooths onto the skin, leaving a soft, elegant finish.
- 20% Zinc Oxide formula calms and soothes
- Sheer, universal tint
- Gentle protection is ideal for post-procedure use and sensitive skin
- Photostable, will not degrade in sunlight
- FREE of chemical sunscreen filters, dyes, fragrances, oils and preservatives
- Reef Friendly
“I’ve been using TIZO sunscreens for nearly 10 years and just love them! They have amazing tinted and non-tinted options. I usually go for tinted if I’m headed out for an event or after I’ve had any aggressive treatments done. If I’m headed out for a bike ride, to the gym, or to the beach, I opt for non-tinted! The whole line is cosmetically elegant and offers great coverage.” Barry Eichner
Don’t forget to remind your patients to ensure they cleanse their skin after a day in the sun! This helps to clear out dirt and debris from the pores. The TIZO® Gentle Amino Gel Cleanser is ideal for all skin types, including sensitive skin. Contains a nourishing blend of 11 amino acids formulated in a clear, gentle gel that hydrates and soothes as it cleanses. Created with plant-based cleansing ingredients, TIZO® Gentle Amino Gel Cleanser effectively removes makeup and impurities from the skin with a light lather, leaving skin soft, supple, and radiant. Contains no sulfates, parabens, dyes, or fragrances.
Radio Frequency Machine by ThermoClear USA
This is a Class 1 Non-Medical Device. It’s truly remarkable! Medical + spa skin care professionals can now help clients eliminate unwanted skin imperfections! This is an opportunity to help clients achieve smooth, even-toned skin that is free from epidermal skin imperfections such as small spider capillaries, cherry angiomas, milia, acne, skin tags, sebaceous hyperplasia, fibromas, cholesterol deposits, sun and age spots.
ThermoClear USA utilizes a unique science that’s a combination of both low and high radio frequency technology that can treat most skin types.
ThermoClear treatments can treat skin irregularities on:
- Face
- Neck
- Decollette
- Shoulders
- Hands
- Arms
- Back
ThermoClear Machines typically require one treatment, and the results are instantaneous. ThermoClear systems are backed by Doctors and Estheticians and come with a Lifetime Warranty. We also provide full training and ongoing support.
All-New SVEN by ZAQ
ZAQ SVEN – where beauty meets innovation!
The latest in handheld device technology from ZAQ, a large medical + spa skin care device manufacturer. The all-new SVEN is a multi-functional device that has RF, Microcurrent, Red Light, and 3D Massage Technology.
Help your patients unlock radiance and embrace renewal! The RF technology will help to tighten and rejuvenate the skin. The SVEN has microcurrent technology for improved tone & contour. It also offers Red Light Therapy for collagen production & fine-line reduction. It has 3D technology for enhanced absorption & massage effects and 3D massage head for deep tissue stimulation & relaxation.
“This handheld device is so soothing, and I love using this around the eye area at the end of the day. The cool stainless steel is so refreshing, and the massaging motions help de-puff the area.” Jenni Nagle
