This past September I presented on PDRN technology at the AAMC in Orlando, FL to physicians from all over the world in aesthetic medicine. Some had never heard of a salmon sperm facial while others from Venezuela, Ukraine, and Italy had been using it in their clinics for years. The US has been slowly but surely coming around to the technology that has been utilized in Korea and other parts of the world. PDRN has been a staple in Korean skin care for over 10 years. Korean skincare principles emphasize harmonizing with the natural environment, prioritizing skin health by reinforcing the barrier and maintaining intense hydration. This philosophy is deeply rooted in achieving long-term skin health rather than seeking quick fixes. By focusing on hydration and barrier repair, Korean skincare practices support the skin’s microbiome, reduce inflammation, and optimize cellular functions.
But why does this matter to you as a nurse injector or aesthetician? Understanding and incorporating these principles into your practice can significantly enhance patient outcomes and satisfaction. Supporting cellular health with innovative treatments, such as those containing PDRN (polydeoxyribonucleotide), takes these principles a step further, offering cutting-edge solutions for anti-aging, rejuvenation, and recovery.
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Science Behind PDRN: A Game-Changer in Skin Rejuvenation
PDRN is a snippet of DNA that is virtually identical to human DNA in its rejuvenative coding. It promotes cellular turnover, angiogenesis (the formation of new blood vessels), and fibroblast activation—all of which are critical for collagen synthesis and skin repair. PDRN also downregulates reactive oxygen species (ROS) and lowers inflammation, making it a powerful agent for cellular health and anti-aging.
While PDRN is most effective when injected, it also shows significant benefits as a topical treatment. When used topically, PDRN can enhance post-procedure recovery, boost hydration, and reinforce the skin’s barrier. These effects make it an essential component of modern skincare regimens.
Timing Matters: Consistency is Key
To achieve optimal results with PDRN, regular treatments are essential. A single treatment can provide noticeable improvements, but long-term benefits arise from a series of applications. Whether injected or applied topically, PDRN works best when introduced into the skin regularly, allowing it to build up and support ongoing cellular repair and rejuvenation.
Dr. Chantal Lunderville, L+A Medical + Wellness Editor
Dr. Chantal Lunderville is a board-certified physician specializing in skin health, aesthetic medicine, and Women’s health. She attended medical school at UCLA School of Medicine, followed by a residency at UCSF Family Medicine, and on graduating opened her own concierge aesthetics practice in the San Francisco Bay Area focusing on hormone health, skincare, and longevity.
Since then Dr. Lunderville has grown her practice to include overseeing nurses and aestheticians as medical director to over 15 practices across California, and through Dr. C’s Academy helps to launch new practices across the US and Canada through consulting and online courses in business, compliance, aesthetic procedures including neurotoxin, fillers, lasers, microneedling, and lasers. Read Full Bio
Cellular Health: The Foundation of Youthful Skin
As we study aging, we’ve identified pathways affected by damage and time that determine how skin looks, heals, and repairs itself. One key player in this process is reactive oxidative species (ROS). These molecules, byproducts of cellular metabolism, are the waste products of our cellsl. Even healthy processes generate some “trash,” but without proper management, this trash accumulates and disrupts cellular functions.
So, how can we recycle or “compost” this waste rather than allowing it to harm our skin’s ecosystem? PDRN provides a solution by enhancing cellular repair mechanisms, reducing ROS damage, and supporting the pathways that maintain healthy, resilient skin. With consistent use, PDRN can help rejuvenate skin at a cellular level, offering visible and lasting improvements.
How Can You Use PDRN in Practice?
For Aestheticians:
- Familiarize Yourself with PDRN-Containing Products
- Incorporate products like Nelly DeVuyst’s Lifting Complex Serum or Rejuran retail PDRN products into your anti-aging regimens. These products can provide your clients with a powerful tool for enhancing skin health at home.
- Post-Procedure Application
- Use PDRN immediately following microneedling or laser treatments to accelerate recovery and optimize results. For the first 24 hours, recommend applying PDRN-containing products every few hours at home to maximize healing.
- Educate Clients on Consistency
- Highlight the importance of regular use for long-term benefits. Explain that PDRN works cumulatively, building up the skin’s resilience and repair mechanisms over time.
For Injectors:
Combine PDRN treatments with other procedures such as neurotoxins or fillers to enhance overall patient outcomes. By addressing cellular health, you’re building a foundation for better results from other interventions.
Injection Treatments
While PDRN injections are not FDA-approved in the U.S., they are used in other countries to rejuvenate skin through superficial injections every 4-6 weeks. These treatments stimulate collagen production and repair, offering a unique, science-backed approach to anti-aging.
Synergistic Approach
Combine PDRN treatments with other procedures such as neurotoxins or fillers to enhance overall patient outcomes. By addressing cellular health, you’re building a foundation for better results from other interventions.
PDRN represents a fusion of Korean skincare principles and advanced science, offering a holistic approach to skin health. By reinforcing the skin barrier, boosting hydration, and addressing cellular damage, PDRN helps aestheticians and nurse injectors provide patients with unparalleled care. Whether used topically or through injection, PDRN is a versatile tool that aligns with the goals of long-term skin health and rejuvenation. As practitioners, incorporating PDRN into your practice not only elevates patient care but also positions you at the forefront of aesthetic innovation.
References
[1] Front. Pharmacol., 25 April 2017. Sec. Integrative and Regenerative Pharmacology Volume 8 – 2017 | https://doi.org/10.3389/fphar.2017.00224